Gifford Lab @ Stanford
Selected publications relevant to our current research:
A lethal mitonuclear incompatibility in complex I of natural hybrids
Moran B, Payne C, et al. Nature volume 626, pages119–127 (2024)
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Single-cell multimodal analyses reveal epigenomic and transcriptomic basis for birth defects in maternal diabetes
Nishino T, Ranade SS, Pelonero A, et al. Nature Cardiovascular Research. 2023 Nov 30; 2: 1990-1203
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The multi-lineage transcription factor ISL1 controls cardiomyocyte cell fate through interaction with NKX2.5.
Maven BEJ, Gifford CA, et al. Stem Cell Reports. 2023 Nov 14;18(11):2138-2153
Beyond the exome: What's next in diagnostic testing for Mendelian conditions.
Wojcik MH, Reuter CM, Marwaha S, et al. Am J Hum Genet. 2023 Aug 3;110(8):1229-1248
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Transcription factor protein interactomes reveal genetic determinants in heart disease.
Gonzalez-Teran B, Pittman M, Felix F, et al. Cell. 2022 Mar 3;185(5):794-814.e30
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Network-based screen in iPSC-derived cells reveals therapeutic candidate for heart valve disease.
Theodoris CV, Zhou P, et al. 2021 Feb 12;371(6530)
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Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects.
de Soysa TY, Ranade SS, et al.Nature. 2019 Aug;572(7767):120-124
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Context-Specific Transcription Factor Functions Regulate Epigenomic and Transcriptional Dynamics during Cardiac Reprogramming.
Stone NR, Gifford CA, Thomas R, et al. Cell Stem Cell. 2019 Jul 3;25(1):87-102
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Oligogenic inheritance of a human heart disease involving a genetic modifier.
Gifford CA, Ranade SS, Samarakoon R, et al. Science. 2019 May 31;364(6443):865-870
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Genetic determinants and epigenetic effects of pioneer-factor occupancy.
Donaghey J, Thakurela S, Charlton J, et al. Nat Genet. 2018 Feb;50(2):250-258
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Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells.
Liao J, Karnik R, Gu H, et al.Nat Genet. 2015 May;47(5):469-78
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Transcriptional and epigenetic dynamics during specification of human embryonic stem cells.
Gifford CA, Ziller MJ, Gu H, et al. Cell. 2013 May 23;153(5):1149-63
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